- Original Article
- Neonatology (Perinatology)
- Clinical features and prognostic factors of early-onset sepsis: a 7.5-year experience in one neonatal intensive care unit
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Se Jin Kim, Ga Eun Kim, Jae Hyun Park, Sang Lak Lee, Chun Soo Kim
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Clin Exp Pediatr. 2019;62(1):36-41. Published online September 27, 2018
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Purpose: In this study, we investigated the clinical features and prognostic factors of early-onset sepsis (EOS) in neonatal intensive care unit (NICU) patients.
Methods: A retrospective analysis was conducted on medical records from January 2010 to June 2017 (7.5 years) of a university hospital NICU.
Results: There were 45 cases of EOS (1.2%) in 3,862 infants. The most common pathogen responsible for... |
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- Nephrology (Genitourinary)
- Diagnostic accuracy of urinary biomarkers in infants younger than 3 months with urinary tract infection
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Nani Jung, Hye Jin Byun, Jae Hyun Park, Joon Sik Kim, Hae Won Kim, Ji Yong Ha
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Clin Exp Pediatr. 2018;61(1):24-29. Published online January 22, 2018
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Purpose The aim of this study was to evaluate the diagnostic accuracy of urinary biomarkers, such as neutrophil gelatinase-associated lipocalin (uNGAL) and β-2 microglobulin (uB2MG), in early detection of urinary tract infection (UTI) in infants aged <3 months with fever. MethodsA total of 422 infants aged <3 months (male:female=267:155; mean age, 56.4 days), who were admitted for fever, were retrospectively included in... |
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- Neonatology (Perinatology)
- Neuroprotective effects of erythropoietin against hypoxic injury via modulation of the mitogen-activated protein kinase pathway and apoptosis
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Ji Eun Jeong, Jae Hyun Park, Chun Soo Kim, Sang Lak Lee, Hai Lee Chung, Woo Taek Kim, Eun Joo Lee
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Clin Exp Pediatr. 2017;60(6):181-188. Published online June 22, 2017
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Purpose Hypoxic-ischemic encephalopathy is a significant cause of neonatal morbidity and mortality. Erythropoietin (EPO) is emerging as a therapeutic candidate for neuroprotection. Therefore, this study was designed to determine the neuroprotective role of recombinant human EPO (rHuEPO) and the possible mechanisms by which mitogen-activated protein kinase (MAPK) signaling pathway including extracellular signal-regulated kinase (ERK1/2), JNK, and p38 MAPK is modulated in... |
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- Pseudomembranous colitis in children: Experience of a university hospital in Korea
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Jae Hyun Park, Kyung Ji Kang, Yu Na Kang, Ae Suk Kim, Jin-Bok Hwang
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Clin Exp Pediatr. 2010;53(2):184-189. Published online February 15, 2010
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Purpose : Pseudomembranous colitis (PMC) occurs rarely in children, but its incidences are increasing due to frequent antibiotic use. We investigated the incidence and clinical characteristics of PMC accompanied by bacterial enteritis-like symptoms in children.
Methods : Between November 2003 and July 2007 at the Department of Pediatrics, Dongsan Medical Center, we analyzed the medical records of consecutive patients who received... |
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- Clinical Characteristics of Complex Partial Seizures : a Temporal versus a Frontal Lobe Onset
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Joon Soo Lee, Jae Hyun Park, Chang Jun Coe
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Clin Exp Pediatr. 1998;41(6):769-774. Published online June 15, 1998
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Purpose : This study was performed to correlate clinical behaviours with either a temporal or
frontal site of origin and then to identify behaviours that might have a significant practical value
in differentiating a temporal from a frontal focus and thus reduce the need for invasive
monitoring.
Methods : We analysed 129 seizures that occured during video-EEG monitoring in 13 patients
with temporal lobe epilepsy(TLE)... |
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- Etiological Analysis of Gynecomastia in Children
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Jai Keun Kim, Ki Keun Oh, Choon Sik Yoon, Jae Hyun Park
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Clin Exp Pediatr. 1998;41(2):224-229. Published online February 15, 1998
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Purpose : The purpose of this study is to analyze the etiology of gynecomastia confirmed by breast operation among children under the age of 15 exhibiting clinical symptoms.
Methods : Twenty patients under the age of 15 were diagnosed as having gynecomastia in the past 10 years. The number of pathologically confirmed gynecomastia patients was 15. The causes or related... |
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